SeroLean Review

Full Review

SeroLean is a science-backed dietary supplement that reprograms the brain to allow the body to easily and often, effortlessly burn fat 24/7. The supplement is made with clinically proven, all-natural ingredients that work with your body's natural rhythms to increase serotonin levels, optimize your metabolism, and facilitates weight management.

  • Creator: SeroLean
  • Contents: supplement
  • Price: $39 / $49 / $59
  • Official Website:
Visit Official Website

SeroLean is a dietary supplement by SeroGenesis that is formulated to rewire the brain to enable the body to easily burn off a significant amount of fat, for effortless and continuous weight loss. It’s a game-changing supplement that’s supported by all kinds of scientific research and endorsed by some of the top doctors across the nation. Its innovative approach goes beyond conventional weight loss methods, using all natural ingredients to align the brain with your body's natural rhythms. By doing so, you’ll be increasing serotonin levels, optimizing your metabolism and burning fat 24/7, allowing for sustainable weight control. Over 24,000 people have used this all-natural approach to achieve weight loss, with the averaging being 35 lbs in just 12 weeks. There are no pills, calorie counting, exhausting exercise routines, or restrictive diets required either. It's all in the natural formula that optimizes your mind and body for long-term weight management.

The Ingredients

How It Works

The way the SeroLean supplement works comes down to a science.

Serotonin is brain chemical commonly referred to as your "feel-good" neurotransmitter. It plays a significant role in appetite regulation and mood stabilization. When serotonin levels are optimal, they can help reduce excessive food cravings, particularly for carbohydrates. This is because serotonin helps signal to the brain that the body is satiated, reducing the urge to overeat.

However, when serotonin levels are low, it can lead to increased feelings of sadness, irritability, stress and anxiety. This often results in emotional or “comfort” eating, a behaviour wherein individuals seek out high-calorie, carbohydrate-rich foods to provide a temporary feeling of relief. These foods can cause a short-term boost in serotonin levels, which can alleviate negative feelings for the time being. However, the long-term consequence is often weight gain due to the excessive calorie consumption.

The good news is that maintaining adequate serotonin levels can enhance mood and overall well-being. This can help combat weight in a variety of ways. For example, with higher serotonin levels, you will likely experience fewer cravings for high-calorie, carby foods. The boost in your mood can help avoid emotional eating and help you feel more motivated to engage in regular physical activity and make healthier food choices.

Put all of this together and maintaining optimal serotonin levels can influence your appetite, cravings, mood, and behaviour, all of which contribute to weight management and weight loss efforts.

And that’s where SeroLean is the answer. It is formulated to solve the serotonin issue, using all high quality ingredients that naturally boost this “feel good” hormone. And since it’s made with a premium blend of natural ingredients, this supplement also offers many additional health benefits.

To fully understand the benefits of this supplement and how it works, let’s take a look at some of the ingredient highlights.

Outline of the Supplement

Stinging Nettle Leaf

Stinging nettle leaf is known for its anti-inflammatory properties, which can potentially aid in conditions like osteoarthritis and hay fever. It can also regulate blood sugar in type 2 diabetics, and act as a diuretic to help flush out excess fluids. Additionally, nettle leaves are nutritionally rich, containing vitamins and minerals such as vitamin C, vitamin A, calcium, magnesium, and iron.

The leaf’s hairs also contains serotonin, which can help boost your serotonin levels.

Green Tea Extract

Green tea extract is rich in polyphenols, particularly catechins like epigallocatechin gallate (EGCG). These compounds are highly recognized for their antioxidant properties, which can combat oxidative stress and cellular damage.

Additionally, green tea extract has been associated with several health benefits including enhanced metabolic rate, promotes fat oxidation, improved heart health, and support for cognitive function.

Some studies hint at green tea's ability to modulate neurotransmitters as well, potentially impacting your mood. When your mood is increased, this can reduce emotional eating, a frequent challenge in weight management.


The supplement’s website talks a lot about the Griffonia Simplicifolia plant and it being leading ingredient in SeroLean. This is because the seeds from this plant are rich in 5-Hydroxytryptophan (5-HTP), a precursor to the mood-regulating neurotransmitter: serotonin. As mentioned, serotonin is vital for mood, appetite, and sleep, all of which play a factor in weight management.

In fact, supplementing with 5-HTP has been associated with mood enhancement, which may help alleviate symptoms of depression. As such, it has the potential to prevent emotional eating and unhealthy cravings, which can aid weight loss efforts.

Additionally, by influencing serotonin levels, which is a precursor to the sleep hormone melatonin, 5-HTP may also support improved sleep patterns. Quality of sleep plays a major factor in weight management, offering yet another avenue that this supplement can help you achieve weight loss.


Caffeine can elevate mood by facilitating the release of certain neurotransmitters like dopamine and norepinephrine. Some studies suggest that caffeine contains neuroprotective effects as well, which help protect against diseases such as Alzheimer's and Parkinson's.

Caffeine is also known for naturally accelerating metabolism, leading to an increased rate of calorie burning. It mobilizes fatty acids from fat tissues as well, making them more available for energy use allowing you to burn more fat for energy. Some studies have also shown caffeine can help reduce appetite by suppressing appetite and enhancing satiety, potentially reducing calorie intake.

Saffron Extract

Saffron has been linked to offering a range of health benefits, including mood enhancement, improved visual function, and antioxidant properties that combat oxidative stress. Its bioactive compounds, particularly crocetin and safranal, contribute to these effects.

Saffron is also believed to influence serotonin levels in the brain. Serotonin plays a pivotal role in mood regulation, and an increase in its levels can lead to mood enhancement and reduced symptoms of depression. This influence on serotonin is also associated with appetite suppression. Some studies have confirmed that saffron can reduce feelings of hunger and decrease snacking frequency, particularly in those who engage in emotional eating.


L-Tryptophan is one of the essential amino acids, meaning our bodies cannot produce it and we must obtain it from our diet. This amino acid plays several crucial roles in human health. Apart from being a building block of proteins, L-Tryptophan is a precursor to several important molecules, including niacin (vitamin B3) which is vital for energy metabolism, and the neurotransmitter serotonin.

Inside the body, L-Tryptophan is converted into 5-Hydroxytryptophan (5-HTP) by an enzyme, and 5-HTP, in turn, is converted into serotonin. By being a primary precursor, L-Tryptophan indirectly supports positive mood, balanced appetite, and healthy sleep cycles. In fact, it can be so effective that supplements containing L-Tryptophan are often used as a natural way to address conditions like insomnia, depression, and anxiety.


Magnesium is a crucial mineral that supports numerous physiological functions, including muscle and nerve activity, bone health, and energy creation. It also plays many roles in heart health, can help reduce migraines and many studies have confirmed its potential for mood regulation.

In relation to serotonin, magnesium helps produce and regulate this neurotransmitter.

On the other hand, low magnesium levels can diminish serotonin, negatively impacting mood and behavior. For example, the lower your magnesium levels, the quicker you go through serotonin. This can lead to a lack of serotonin, which increases your stress levels and the higher your stress levels, the quicker you go through magnesium. This creates a continuous cycle of stress, anxiety, low serotonin and low magnesium. So, supplementing magnesium is key for keeping everything in balance.

Vitamin B3

Vitamin B3, also known as niacin, is an essential nutrient that have various roles in the body. It aids in converting food into energy by supporting enzymes that drive cellular metabolism. It’s also crucial for the health of the nervous system, skin, and digestive system. Niacin contributes to proper brain function too and can also help lower LDL cholesterol levels while increasing HDL cholesterol, promoting overall heart health.

Niacin also plays a role in serotonin production. Tryptophan, an amino acid, can be converted into niacin in the body if you’re low in niacin. On the other hand, when niacin levels are sufficient, tryptophan is more likely to be directed towards the production of serotonin. The good news is SeroLean has both of these in the right amounts for your body to focus on serotonin production and regulation.

Vitamin B6

Vitamin B6 plays a key role in amino acid metabolism, red blood cell formation, and the production of neurotransmitters. It is vital for brain development and function, and helps the body convert food into energy. This vitamin also contributes to maintaining the health of the nervous system and supporting immune function.

Vitamin B6 is directly involved in serotonin production too. It acts as a coenzyme for enzymes that convert the amino acid tryptophan into serotonin. Thus, adequate levels of Vitamin B6 ensures efficient production of serotonin.


Chromium is an essential trace mineral vital for the metabolism of nutrients in the body. It is particularly important for the metabolism of carbohydrates, aiding in the function of insulin—a hormone crucial for regulating blood sugar levels. By enhancing the action of insulin, chromium helps ensure that glucose is efficiently transported into cells, where it's used for energy. This role in glucose metabolism contributes to the body's overall energy balance and can impact muscle growth and fat storage.

Some studies also suggest that chromium supplementation can help reduce food cravings, appetite, and fat storage.

As you can see from the above, SeroLean is formulated with the best ingredients to help regulate and boost your serotonin levels naturally. And with adequate serotonin, you’ll be supporting mood stability, reducing the risk of depression and anxiety, regulating appetite, promoting feelings of satiety, and ensuring healthy sleep cycles. All of these factors play a major part in weight management.

And remember, not only do the ingredients help boost serotonin levels, they also come with many other benefits such as regulating blood sugar levels, improve cholesterol levels, boosting brain health and regulate mood, improving sleep, and many more. Additionally, the ingredients we’ve touched on are just a partial list of all the ingredients. You can imagine how many more benefits you’re going to get from the rest.

The best part is you can reap all these benefits by just taking 2 capsules in the morning before meal, and see the results unfold!


When you order 3 or more bottles, you’re entitled to the following bonuses:

If you opt for the 6 bottle option, you also receive free shipping and another additional bottle of SeroLeanPM.

Advantages of SeroLean

Disadvantages of SeroLean

My Thoughts

SeroLean is a scientifically-backed supplement redefines the approach to fat burning by harmonizing with the body's natural processes. Unlike traditional methods, SeroLean eliminates the need for unconventional pills, calorie counting, strenuous exercise, and restrictive diets. Instead, it leverages a blend of clinically proven, all-natural ingredients that work synergistically with your body to optimize metabolism and boost serotonin levels. By doing so, you can improve and stabilize your mood, reduce cravings, regulate appetite, promote feelings of satiety and enhance your sleep quality. All of these factors play a major role in weight loss and weight management. But that’s not all: by increasing your serotonin levels, you can also reduce the risk of depression and anxiety, regulate blood sugar levels, improve cholesterol levels, boost brain health and so much more. So, if you’re looking for a weight loss solution that is all-natural, backed by science, endorsed by doctors and proven to work, SeroLean, on average, can help you shed of 35 lbs shed in just 12 weeks. And that’s just the starting effects of this supplement that can lead to long-term weight control.

Yes, I Want My Bottle!

Frequently Asked Questions

This supplement is made in a FDA-certified facility with GMP certification, that abides to FDA’s regulation and standards. This means the product is safe and does not contain any contaminants or toxins. Additionally, if there were any issues it would have been recalled by the FDA a long time ago.

However, as always, you may want to speak with a doctor first, especially if you have any underlying health condition or on medication (such as antidepressants). You can also use WebMD interaction checker to see if any of the ingredients listed in the product may interact with your medication.
Due to the popularity of this supplement, there are some counterfeits and fakes that have popped up online. It’s important to avoid these, as you can’t be sure they are manufactured in a FDA-approved facility, are they safe or even effective.

As such, it’s highly recommended to only get the product from the official website. This is the only way to ensure the genuine product.
There is no discount or promo available at the moment. If you come across a website that is offering one, it is likely fake. Triple check the website you’re on and make sure you are on the official website for this supplement.

The product does offer a 60-days money back guarantee.
The product is sold exclusively on their official website. You won’t find it in any stores or on other online websites.. If you happen to see one selling elsewhere (such as Amazon) it is likely fake or probably a counterfeit.
You will not receive any additional benefit by taking more than what’s directed. It is best to stick to what’s directed to avoid any unwanted and potential side-effects.
Check Out SeroLean (Official Website)

Reviewed By
Author Bio Photo

Reba is a licensed registered dietitian in private practice in Nashville, TN and has been the recipient of an Academy of Nutrition and Dietetics “Excellence in Practice” Award. In order to assist her clients with the process of transferring knowledge into action, Reba obtained a Master of Public Health degree with an emphasis in behavioral counseling.

She is an Adjunct Assistant Professor for the School of Nursing at Vanderbilt University.

She lives in Nashville with her husband, Kevin, and their two cats. Reba enjoys an active lifestyle that includes walking, zumba, and ballroom dancing.